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Nov 06, 2018 · There are many studies involving weight loss supplements, but the effect of these supplements on improving leptin resistance and appetite remains unclear (8, 9, 10, 11). Dietary supplements in weight reduction. Dwyer JT(1), Allison DB, Coates PM. Author information: (1)Office of Dietary Supplements, National Institutes of Health, Bethesda, Maryland 20892, USA. DwyerJ1@od.nih.gov We summarize evidence on the role of dietary supplements in weight reduction, with particular attention to their safety and benefits.

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